Every day now for two years I get unsolicited telemarketing calls.........................…

These are all to sell me prescription drugs after I bought 1 stupidly online 2 years ago--a muscle relaxer for my back. They call 7 00 am and 3- 4 times a day. Home run business so I canot change my phone number and the features of unidentified call block dont work anymore ! Anyone have any ideas? PLEASE no joke answers. This is a serious problem as they wake me up and beep in on my business calls etc etc and am at my wits end. If you have a funny answer that WORKS thats ok. NOTHING I HAVE SAID STOPS THEM